Prédiction de structures secondaires
MÃ©thode de prÃ©diction de la structure secondaire des protÃ©ines Ã partir de la sÃ©quence en acides aminÃ©s.
|Run Unix # gorIV||Run Web #|
PSIPRED is a simple and reliable secondary structure prediction method, incorporating two feed-forward neural networks which perform an analysis on output obtained from PSI-BLAST (Position Specific Iterated - BLAST).Version 2.0 of PSIPRED includes a new algorithm which averages the output from up to 4 separate neural networks in the prediction process to further increase prediction accuracy.
Remarque Utilsie les sorties de psiblast
|Run Unix # psipred||Run Web #|
TM-align is an algorithm for sequence-order independent protein structure comparisons. For two protein structures of unknown equivalence, TM-align first generates optimized residue-to-residue alignment based on structural similarity using dynamic programming iterations. An optimal superposition of the two structures, as well as the TM-score value which scales the structural similarity, will be returned. TM-score has the value in (0,1], where 1 indicates a perfect match between two structures. Following strict statistics of structures in the PDB, scores below 0.2 corresponds to randomly chosen unrelated proteins whereas with a score higher than 0.5 assume generally the same fold in SCOP/CATH.
|Run Unix # TMalign PDB1.pdb PDB2.pdb [Options]||Run Web #|